Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 240
interventional 198
Observational 38
Registry 4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 77
Drug|placebo 72
Behavioral 11
Other 7
Device 6
Dietary Supplement|placebo 4
Drug|Procedure 4
Drug|Other 3
Biological 2
Biological|placebo 2
Dietary Supplement 2
Behavioral|Drug 1
Biological|Other 1
Device|Drug|Other 1
Dietary Supplement|Drug 1
Dietary Supplement|Drug|placebo 1
Dietary Supplement|Other|placebo 1
Other|placebo 1
Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 46
China 14
Japan 14
Denmark 11
NA 11
Iran, Islamic Republic of 8
Netherlands 6
Egypt 5
Mexico 5
Brazil 4
Australia 3
Canada 3
France 3
Germany 3
Korea, Republic of 3
Taiwan 3
Hong Kong 2
India 2
Singapore 2
Spain 2
Switzerland 2
Turkey 2
United States|Puerto Rico 2
Australia|New Zealand 1
Austria 1
Austria|Brazil|Czech Republic|Denmark|Finland|Germany|Greece|Hungary|Italy|Mexico|Poland|Russian Federation|Singapore|Spain|Sweden|Thailand|United Kingdom 1
Belgium|Czech Republic|Germany|Hungary|Poland|United Kingdom 1
Belgium|Czechia|Denmark|Germany|Greece|Italy|Macedonia, The Former Yugoslav Republic of|Netherlands|Spain|United Kingdom 1
Belgium|France 1
Bulgaria|Czech Republic|Hungary|Poland|Romania|Slovakia 1
Bulgaria|Denmark|Finland|Israel|Italy|Spain|Sweden 1
Bulgaria|Hungary|Lithuania|Romania|Slovakia 1
China|Japan 1
Croatia|Georgia|Hungary|Serbia|Slovenia 1
Greece|United States|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Chile|China|Colombia|Czechia|Denmark|Finland|France|Germany|Hong Kong|Hungary|Ireland|Israel|Italy|Japan|Korea, Republic of|Lithuania|Malaysia|Mexico|Netherlands|New Zealand|Norway|Philippines|Poland|Portugal|Puerto Rico|Romania|Russian Federation|Saudi Arabia|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|Turkey|Ukraine|United Kingdom|Vietnam 1
Ireland 1
Ireland|Italy|United Kingdom 1
Italy 1
Italy|Slovenia 1
Japan|Serbia|Slovakia|India|United States|Argentina|Australia|Brazil|Bulgaria|Canada|Chile|China|Colombia|Czechia|France|Germany|Guatemala|Hungary|Korea, Republic of|Lithuania|Malaysia|Mexico|New Zealand|Philippines|Poland|Puerto Rico|Romania|Russian Federation|South Africa|Spain|Taiwan|Ukraine|United Arab Emirates|United Kingdom 1
Qatar 1
Romania 1
Slovakia|Spain|Czech Republic|Estonia|Germany|Netherlands|Poland 1
Taiwan|France|Spain|Czech Republic|Denmark|Germany|Italy|Korea, Republic of|Malaysia|Portugal|Russian Federation|Slovakia|Ukraine 1
Taiwan|United States|Australia|Austria|Bulgaria|Canada|Czech Republic|Denmark|Finland|France|Germany|Hong Kong|Hungary|Israel|Italy|Korea, Republic of|Netherlands|Norway|Poland|Portugal|South Africa|Spain|Sweden 1
Thailand 1
United Kingdom 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Chile|China|Colombia|Czechia|Denmark|Finland|France|Germany|Greece|Hong Kong|Hungary|Ireland|Israel|Italy|Japan|Korea, Republic of|Lithuania|Malaysia|Mexico|Netherlands|New Zealand|Norway|Philippines|Poland|Portugal|Puerto Rico|Romania|Russian Federation|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|Turkey|Ukraine|United Kingdom|Vietnam 1
United States|Argentina|Australia|Canada|Germany|Hong Kong|Italy|Korea, Republic of|Malaysia|Peru|Poland|Puerto Rico|Romania|Spain 1
United States|Argentina|Czechia|Germany|Jordan|Lebanon|Turkey 1
United States|Australia|Canada|Czech Republic|Germany|Poland 1
United States|Australia|Canada|Denmark|Hong Kong|India|Korea, Republic of|Malaysia|Mexico|Poland|Serbia|Slovakia|South Africa|Sweden|United Kingdom 1
United States|Australia|Netherlands 1
United States|Belgium|Canada|Czechia|Germany 1
United States|Bulgaria 1
United States|Canada 1
United States|Canada|Australia|Japan|New Zealand 1
United States|Canada|Denmark 1
United States|Canada|Denmark|France|Germany|Greece|Italy|Netherlands|Romania|Russian Federation|Spain|United Kingdom 1
United States|Canada|Puerto Rico|Taiwan 1
United States|Germany|Greece|Italy|Netherlands|Poland|Portugal|Puerto Rico|Spain|Taiwan 1
United States|Japan 1
United States|Japan|Mexico|Puerto Rico 1
United States|New Zealand 1
United States|Taiwan|Argentina|Australia|Brazil|Canada|Korea, Republic of|Mexico|New Zealand|Thailand 1

Sites per Study

Site_count Study_Count
1 130
2 8
3 5
4 1
6 4
7 2
10 1
12 1
13 1
14 1
15 2
16 3
18 2
19 1
20 1
24 1
26 1
27 2
28 2
30 1
34 1
35 1
37 1
42 1
43 2
45 2
47 1
48 1
49 1
50 1
54 1
63 1
72 2
83 1
105 1
109 1
111 1
142 1
160 2
168 1
190 1
593 1
972 1
973 1

Phase

Phase Study_Count
Phase 2 63
N/A 43
Phase 4 38
Phase 3 24
Phase 1/Phase 2 11
Phase 2/Phase 3 9
Phase 1 7
Early Phase 1 3

Number of Arms

Number_of_Arms Count_of_Studies
1 17
2 97
3 27
4 17
5 4
6 2
8 3
NA 31

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 60 10.0000 6.00000 24.00 10.0000 22.0000 16.00 15.0000
1st Qu. 102 37.0000 25.00000 30.25 50.2500 60.0000 113.75 44.2500
Median 144 63.5000 38.00000 45.00 109.0000 100.0000 300.00 66.0000
Mean 116 136.7381 38.14286 44.30 140.9839 283.8889 1154.25 217.2632
3rd Qu. 144 128.7500 49.00000 50.75 167.2500 148.0000 841.50 123.0000
Max. 144 1312.0000 75.00000 77.00 823.0000 1777.0000 7437.00 2510.0000

Trial Group Type

group_type Group_Count
Experimental 205
Placebo Comparator 94
Active Comparator 85
NA 31
No Intervention 17
Other 11
Sham Comparator 4

Intervention Model

intervention_model Study_Count
Parallel Assignment 157
Single Group Assignment 22
Crossover Assignment 16
Factorial Assignment 1
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 166
Prevention 19
Diagnostic 5
Basic Science 2
Other 2
NA 2
Health Services Research 1
Supportive Care 1

Observational Studies

Studies by Country

Country Study_Count
United States 10
China 4
Denmark 4
NA 3
Brazil 2
Canada 1
Egypt 1
Finland|France|Italy|Sweden|Switzerland|United Kingdom 1
France 1
Germany 1
India 1
Indonesia 1
Ireland 1
Italy 1
Japan 1
Qatar 1
Sweden 1
Switzerland 1
Taiwan 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 33
4 1
5 1
7 1
19 1
21 1

Enrollment Metrics

Measure Observational
Min 17.0000
1st Qu 100.0000
Median 181.0000
Mean 562.4737
3rd Qu 446.0000
Max 9031.0000

Observation Model

observational_model Study_Count
Cohort 14
Case-Control 8
Case Control 6
Case-Only 4
Other 3
NA 2
Defined Population, Natural History 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 14
Prospective 12
Retrospective 8
NA 3
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
China 1
Egypt 1
Italy 1
United States 1

Sites per Study

Site_count Study_Count
1 4

Enrollment Metrics

Measure Registries
Min 68.0
1st Qu 84.5
Median 105.0
Mean 569.5
3rd Qu 590.0
Max 2000.0

Registry Model

observational_model Study_Count
Case-Control 2
Cohort 2

Time Perspective

time_perspective Study_Count
Cross-Sectional 2
Prospective 2

Follow-up

target_duration Study_Count
10 Years 1
12 Months 1
12 Weeks 1
21 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03216564 An Intervention to Examine the Effect of Vitamin D on Urine Protein Levels in Type 2 Diabetes https://ClinicalTrials.gov/show/NCT03216564 Recruiting Hamad Medical Corporation 2019-05-10
NCT03824379 Magnesium Supplementation in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03824379 Recruiting Ain Shams University 2020-03-01
NCT03344549 Effect of the Teleconsultation of Renal Nutrition on Renal Function and Glycemic Control in Patients With DKD https://ClinicalTrials.gov/show/NCT03344549 Completed Hospital Civil Juan I. Menchaca 2019-02-05
NCT03325322 Inflammation and Stem Cells in Diabetic and Chronic Kidney Disease https://ClinicalTrials.gov/show/NCT03325322 Recruiting Mayo Clinic 2023-01-31
NCT03217591 A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria https://ClinicalTrials.gov/show/NCT03217591 Completed Cyclerion Therapeutics 2019-08-20
NCT03184662 Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT03184662 Recruiting Poitiers University Hospital 2022-07-31
NCT03174821 Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03174821 Completed Chinese PLA General Hospital 2014-05-16
NCT03165227 This Study Tests a New Medicine Called BI 685509 in Patients That Have Kidney Problems Because of Diabetes. The Study Tests How BI 685509 is Taken up in the Body and How Well it is Tolerated (Multiple Rising Doses) https://ClinicalTrials.gov/show/NCT03165227 Completed Boehringer Ingelheim 2019-12-10
NCT03164785 Efficacy and Safety of Jinshuibao Capsule on Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03164785 Recruiting Second Xiangya Hospital of Central South University 2018-12-31
NCT03147677 Clinical Study of Treating Type 2 Diabetic Nephropathy With Alfacalcidol and Irbesartan https://ClinicalTrials.gov/show/NCT03147677 Completed The Third Xiangya Hospital of Central South University 2018-07-30
NCT03105219 IvaBradinE to Treat MicroalbumiNuria in Patients With Type 2 Diabetes and Coronary Heart Disease https://ClinicalTrials.gov/show/NCT03105219 Recruiting Nanjing First Hospital, Nanjing Medical University 2021-05-30
NCT03078101 EMPRA (EMPagliflozin and RAs in Kidney Disease) https://ClinicalTrials.gov/show/NCT03078101 Completed Medical University of Vienna 2019-06-18
NCT03006952 Add-on Pentoxifylline to Losartan Versus Increasing Dose of Losartan on NT-PRO BNP in Type 2 Diabetics With Nephropathy https://ClinicalTrials.gov/show/NCT03006952 Completed Tehran University of Medical Sciences 2015-09-30
NCT02928250 Role of Carnosine as an Adjuvant Therapy for Diabetic Nephropathy in Pediatrics With Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02928250 Completed Ain Shams University 2016-05-31
NCT02923063 Exercise Study Testing Enhanced Energetics of Muscle Mitochondria in CKD https://ClinicalTrials.gov/show/NCT02923063 Recruiting University of California, Davis 2021-12-31
NCT02829177 Microalbuminuria and Allopurinol in Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02829177 Completed Steno Diabetes Center Copenhagen 2016-08-10
NCT02816762 CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea https://ClinicalTrials.gov/show/NCT02816762 Active, not recruiting Hospital Universitario La Paz 2020-07-31
NCT02768948 Telmisartan Promotes the Differentiation of Monocytes Into Macrophages M2 in Diabetic Nephropathy? https://ClinicalTrials.gov/show/NCT02768948 Recruiting Centre Hospitalier Universitaire de Nice 2019-07-31
NCT02704494 Resveratrol’s Effects in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02704494 Completed Shiraz University of Medical Sciences 2017-02-28
NCT02690883 Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02690883 Completed Nanfang Hospital of Southern Medical University 2019-12-13
NCT02689778 Effect of Pirfenidone on Glomerular Filtration Rate and Albuminuria in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02689778 Active, not recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 2019-12-31
NCT02676401 An Extended Treatment Study of MT-3995 in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02676401 Completed Mitsubishi Tanabe Pharma Corporation 2017-08-31
NCT02628106 Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02628106 Completed West China Hospital 2016-01-31
NCT02585622 NEPHSTROM for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT02585622 Recruiting Mario Negri Institute for Pharmacological Research 2020-06-30
NCT02682563 Renoprotective Effects of Dapagliflozin in Type 2 Diabetes https://ClinicalTrials.gov/show/NCT02682563 Completed VU University Medical Center 2018-09-30
NCT02552277 A Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects With Diabetic Peripheral Neuropathy https://ClinicalTrials.gov/show/NCT02552277 Completed Celularity Incorporated 2017-03-07
NCT02545738 Antiproteinuric Effects of Liraglutide Treatment https://ClinicalTrials.gov/show/NCT02545738 Completed Steno Diabetes Center Copenhagen 2016-05-31
NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT02545049 Active, not recruiting Bayer 2021-06-21
NCT02540993 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT02540993 Completed Bayer 2020-04-14
NCT02517320 Efficacy and Safety of MT-3995 in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02517320 Completed Mitsubishi Tanabe Pharma Corporation 2016-11-30
NCT02515461 Low Energy Shockwave Therapy (LE-SWT): A Novel Treatment for Chronic Kidney Disease https://ClinicalTrials.gov/show/NCT02515461 Recruiting Odense University Hospital 2022-01-31
NCT02502071 Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02502071 Completed University of Colorado Denver School of Medicine Barbara Davis Center 2017-07-31
NCT02501772 The Evaluation of Effect of Sanyinjiao (SP6) Acupressure on Early Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02501772 Recruiting Mackay Memorial Hospital 2015-08-31
NCT02488252 Semi-individualised Chinese Medicine Treatment as an Adjuvant Management for Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02488252 Active, not recruiting The University of Hong Kong 2020-09-30
NCT02418091 Integrated Population Program for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT02418091 Completed Duke University 2016-09-30
NCT02384902 Effect of Low GI/ Glycemic Load (GL) Diet in Diabetic Nephropathy Patients https://ClinicalTrials.gov/show/NCT02384902 Completed Isfahan University of Medical Sciences 2014-07-31
NCT02345057 A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Type 2 Diabetic Subjects With Microalbuminuria https://ClinicalTrials.gov/show/NCT02345057 Completed Daiichi Sankyo, Inc. 2016-06-30
NCT02327754 Effect of Topiroxostat on Urinary Albumin Excretion Early Stage Diabetic Nephropathy and Hyperuricemia With or Without Gout https://ClinicalTrials.gov/show/NCT02327754 Completed Sanwa Kagaku Kenkyusho Co., Ltd. 2016-12-31
NCT02276196 Effect of LIXIsenatide on the Renal System https://ClinicalTrials.gov/show/NCT02276196 Completed VU University Medical Center 2016-04-30
NCT02251067 Phase 2 Study to Evaluate Safety & Efficacy of VPI-2690B in Diabetic Nephropathy Patients https://ClinicalTrials.gov/show/NCT02251067 Completed Vascular Pharmaceuticals, Inc. 2017-03-31
NCT02205372 Safety, Tolerability and Pharmacokinetic Study of MT-3995 at a Low Dose in Subjects With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02205372 Completed Mitsubishi Tanabe Pharma Corporation 2015-08-31
NCT02194790 Effect of Integrated CKD Care Program in Early Diabetic Nephropathy in Primary Health Care Setting. https://ClinicalTrials.gov/show/NCT02194790 Completed Bhumirajanagarindra Kidney Institute, Thailand 2013-12-31
NCT02177786 Efficacy, Safety, and Tolerability of Selonsertib (GS-4997) in Participants With Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT02177786 Completed Gilead Sciences 2016-07-31
NCT02164279 Validation of Biomarkers of Diabetic Nephropathy in Type I Diabetic Children https://ClinicalTrials.gov/show/NCT02164279 Completed University Hospital, Toulouse 2015-12-31
NCT02112071 Diabetic Kidney Disease: Influence of Exercise Therapy on Physical and Vascular Function. https://ClinicalTrials.gov/show/NCT02112071 Completed University of Minnesota 2012-11-30
NCT02065791 Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02065791 Completed Janssen Research & Development, LLC 2018-10-30
NCT02040441 Proteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With Normoalbuminuria https://ClinicalTrials.gov/show/NCT02040441 Completed Steno Diabetes Center Copenhagen 2018-11-30
NCT02035891 Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and Microalbuminuria https://ClinicalTrials.gov/show/NCT02035891 Active, not recruiting Chongqing Medical University 2019-09-30
NCT02017171 A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes https://ClinicalTrials.gov/show/NCT02017171 Completed Joslin Diabetes Center 2019-07-15
NCT02010242 Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria https://ClinicalTrials.gov/show/NCT02010242 Completed Genkyotex Innovation SAS 2015-02-28
NCT02004327 The Phase I Clinical Study to Evaluate the Pharmacokinetics of Dw1029M in Healthy Male Volunteer https://ClinicalTrials.gov/show/NCT02004327 Completed Dong Wha Pharmaceutical Co. Ltd. 2013-12-31
NCT01968668 Safety and Efficacy of Different Oral Doses of BAY94-8862 in Japanese Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy (ARTS-DN Japan) https://ClinicalTrials.gov/show/NCT01968668 Completed Bayer 2014-10-31
NCT01967901 Impact of Multidisciplinary Self-care Management of Diabetic Nephropathy on Quality of Life, Self-care Behavior, Glycemic Control, and Renal Function. https://ClinicalTrials.gov/show/NCT01967901 Completed University of Applied Sciences of Western Switzerland 2016-02-29
NCT01935167 To Determine the Efficacy and Safety of DW1029M on Microalbuminuria in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01935167 Completed Dong Wha Pharmaceutical Co. Ltd. 2014-08-31
NCT01923597 Effect of Green Tea (Epigallocatechin Gallate) on Albuminuria in Patients With Diabetic Nephropathy. https://ClinicalTrials.gov/show/NCT01923597 Completed University of Campinas, Brazil 2015-03-31
NCT01889277 Safety, Tolerability and Pharmacokinetic Study of MT-3995 in Subjects With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01889277 Completed Mitsubishi Tanabe Pharma Corporation 2015-01-31
NCT01875341 Role of Sleep Apnea and Sympathetic Activity in Resistant Hypertensive Patients. https://ClinicalTrials.gov/show/NCT01875341 Completed Ottawa Hospital Research Institute 2015-02-28
NCT01874431 Safety and Efficacy of Different Oral Doses of BAY94-8862 in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01874431 Completed Bayer 2014-07-31
NCT01847313 The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT01847313 Completed University College Dublin 2015-11-30
NCT01843387 Safety and Efficacy of Mesenchymal Precursor Cells in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01843387 Completed Mesoblast, Ltd. 2014-09-30
NCT01829256 Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) https://ClinicalTrials.gov/show/NCT01829256 Completed Duke University 2018-11-07
NCT01774981 Study of LY3016859 in Participants With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01774981 Completed Eli Lilly and Company 2015-08-31
NCT01756716 A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria and Moderately Decreased GFR https://ClinicalTrials.gov/show/NCT01756716 Completed Mitsubishi Tanabe Pharma Corporation 2014-09-30
NCT01756703 A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria https://ClinicalTrials.gov/show/NCT01756703 Completed Mitsubishi Tanabe Pharma Corporation 2014-08-31
NCT01726816 Efficacy and Safety Study of Probucol in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01726816 Completed Korea Otsuka Pharmaceutical Co., Ltd. 2014-04-30
NCT01712061 A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy https://ClinicalTrials.gov/show/NCT01712061 Completed Pfizer 2014-09-30
NCT01703234 FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients https://ClinicalTrials.gov/show/NCT01703234 Completed Gulhane School of Medicine 2009-03-31
NCT01684722 Vitamin D and Omega-3 Trial to Prevent and Treat Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT01684722 Completed University of Washington 2019-11-08
NCT01683409 A Study to Test Safety and Efficacy of Baricitinib in Participants With Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT01683409 Completed Eli Lilly and Company 2014-09-30
NCT01671969 Very Low Calorie Diet for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT01671969 Completed Indiana University 2014-03-31
NCT01601236 Acthar for Treatment of Proteinuria in Diabetic Nephropathy Patients https://ClinicalTrials.gov/show/NCT01601236 Completed Mallinckrodt 2016-01-31
NCT01588795 Renal Denervation in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01588795 Completed Assistance Publique - Hôpitaux de Paris 2016-01-31
NCT01521910 Effect of Dietary Protein Restriction on Prognosis in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01521910 Completed Steno Diabetes Center Copenhagen 2000-06-30
NCT01493050 The Effects of Sevelamer Carbonate on Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01493050 Completed Icahn School of Medicine at Mount Sinai 2013-12-31
NCT01487109 A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients https://ClinicalTrials.gov/show/NCT01487109 Completed Concert Pharmaceuticals 2015-01-31
NCT01447147 A Study to Evaluate the Safety and Efficacy of CCX140-B in Subjects With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01447147 Completed ChemoCentryx 2014-08-31
NCT01440257 A Study to Evaluate the Effect of CCX140-B on Urinary Albumin Excretion in Subjects With Type 2 Diabetes and Albuminuria https://ClinicalTrials.gov/show/NCT01440257 Completed ChemoCentryx 2013-02-28
NCT01424319 Reducing Residual Albuminuria in Subjects With Diabetes and Nephropathy With Atrasentan https://ClinicalTrials.gov/show/NCT01424319 Completed AbbVie 2012-07-31
NCT01399580 A Prospective, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of Atrasentan, Including Thoracic Bioimpedance, in Type 2 Diabetic Subjects With Nephropathy https://ClinicalTrials.gov/show/NCT01399580 Completed AbbVie 2012-09-30
NCT01371747 Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN) https://ClinicalTrials.gov/show/NCT01371747 Completed Relypsa, Inc. 2013-05-31
NCT01356849 Evaluate the Efficacy and Safety of Once Daily Administration of Atrasentan Tablets (Low and High) Compared to Placebo in Reducing Residual Albuminuria in Type 2 Diabetic Patients With Nephropathy Who Are Treated With the Maximum Tolerated Labeled Dose of a Renin Angiotensin System (RAS) Inhibitor https://ClinicalTrials.gov/show/NCT01356849 Completed AbbVie 2012-08-31
NCT01331317 Effect of a Vitamin D Analogue vs Placebo on p-NT-proBNP in Patients With Type 1 DM and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01331317 Completed Steno Diabetes Center Copenhagen 2012-04-30
NCT01328821 Safety, Tolerability, and Pharmacokinetics (PK) of CTP-499 https://ClinicalTrials.gov/show/NCT01328821 Completed Concert Pharmaceuticals 2011-04-30
NCT01320345 The Fenofibrate And Microvascular Events in Type 1 Diabetes Eye. https://ClinicalTrials.gov/show/NCT01320345 Recruiting University of Sydney 2022-01-31
NCT04224428 Role of Fexofenadine in Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT04224428 Recruiting Tanta University 2020-07-01
NCT04216849 Clinical Study of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Type 2 Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT04216849 Recruiting Shanghai East Hospital 2021-11-01
NCT04170543 A Phase 2a Diabetic Kidney Disease Study https://ClinicalTrials.gov/show/NCT04170543 Active, not recruiting AstraZeneca 2021-10-04
NCT04143412 Efficacy of ACE Inhibitors, MRAs and ACE Inhibitor/ MRA Combination https://ClinicalTrials.gov/show/NCT04143412 Recruiting Beni-Suef University 2020-02-29
NCT04127084 Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT04127084 Recruiting Zhongshan Hospital Xiamen University 2020-10-31
NCT04026165 Efficacy and Safety of Selonsertib in Participants With Moderate to Advanced Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT04026165 Active, not recruiting Gilead Sciences 2024-12-31
NCT03965975 Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device https://ClinicalTrials.gov/show/NCT03965975 Recruiting S-There Technologies SL 2020-03-31
NCT03899883 Uric Acid Lowering Trial in Youth Onset T2D https://ClinicalTrials.gov/show/NCT03899883 Recruiting University of Colorado Denver School of Medicine Barbara Davis Center 2020-05-31
NCT03885362 Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis https://ClinicalTrials.gov/show/NCT03885362 Recruiting Imperial College London 2020-09-30
NCT03878277 Evaluation of Coffee Therapy for Improvement of Renal Oxygenation https://ClinicalTrials.gov/show/NCT03878277 Active, not recruiting University of Colorado Denver School of Medicine Barbara Davis Center 2020-01-21
NCT03840343 Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03840343 Recruiting Mayo Clinic 2024-12-31
NCT03804879 Safety, Tolerability and Efficacy of LMB763 in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03804879 Recruiting Novartis 2021-12-16
NCT03681704 the Integrated Traditional Chinese and Western Medicine Treat Early Stage DKD https://ClinicalTrials.gov/show/NCT03681704 Recruiting Shanghai University of Traditional Chinese Medicine 2021-09-30
NCT03681249 the Integrated Traditional Chinese and Western Medicine Treat Middle Stage DKD https://ClinicalTrials.gov/show/NCT03681249 Recruiting Shanghai University of Traditional Chinese Medicine 2021-09-30
NCT03664414 Pentoxifylline Effect in Patients With Diabetic Nephropathy.(PENFOSIDINE STUDY) https://ClinicalTrials.gov/show/NCT03664414 Recruiting Coordinación de Investigación en Salud, Mexico 2019-07-30
NCT03627715 Safety and Effectiveness of Propagermanium in Diabetic Kidney Disease Participants Receiving Irbesartan https://ClinicalTrials.gov/show/NCT03627715 Active, not recruiting Dimerix Bioscience Pty Ltd 2020-07-31
NCT03625648 Pentoxifylline in Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03625648 Active, not recruiting VA Office of Research and Development 2028-01-03
NCT03622762 Green Tea Extract on Soluble RAGE in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03622762 Recruiting Centro Universitario de Ciencias de la Salud, Mexico 2019-03-15
NCT03620773 Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT03620773 Recruiting University of Colorado Denver School of Medicine Barbara Davis Center 2023-08-31
NCT03618420 Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function https://ClinicalTrials.gov/show/NCT03618420 Active, not recruiting University of Colorado Denver School of Medicine Barbara Davis Center 2019-10-19
NCT03594240 Vitamin B Complex and Diabetic Nephropathy in Type 1 Diabetes https://ClinicalTrials.gov/show/NCT03594240 Completed Ain Shams University 2018-03-01
NCT03573102 Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients https://ClinicalTrials.gov/show/NCT03573102 Recruiting Ain Shams University 2020-06-30
NCT03550443 A Phase 3 Study of Bardoxolone Methyl in Patients With Diabetic Kidney Disease; AYAME Study https://ClinicalTrials.gov/show/NCT03550443 Active, not recruiting Kyowa Kirin Co., Ltd. 2022-03-31
NCT03535935 Efficacy, Safety and Response Predictors of Adjuvant Astragalus Therapy for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03535935 Recruiting The University of Hong Kong 2022-06-30
NCT03449199 Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria https://ClinicalTrials.gov/show/NCT03449199 Completed Teijin America, Inc. 2019-05-07
NCT03445247 Extracorporeal Low-intensity Shockwave in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03445247 Recruiting Chang Gung Memorial Hospital 2019-06-30
NCT03436693 Efficacy and Safety of Canagliflozin (TA-7284) in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03436693 Active, not recruiting Mitsubishi Tanabe Pharma Corporation 2021-09-30
NCT03413215 Effects of Multidisciplinary Intensive Targeted Care in Improving Diabetes Outcomes: a Pilot Study in Singapore https://ClinicalTrials.gov/show/NCT03413215 Recruiting Changi General Hospital 2021-12-31
NCT03412006 A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY1142524 in Patients With Type II Diabetes and a Clinical Diagnosis of Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03412006 Completed Bayer 2019-10-02
NCT01265563 N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01265563 Completed VA Office of Research and Development 2015-02-28
NCT01252056 A Clinical Study to Evaluate the Efficacy and Safety of Cilostazol and Probucol in Combination on Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01252056 Completed Otsuka Beijing Research Institute 2012-12-31
NCT01214356 Impact of Vitamin D on Diabetic Kidney Disease in African Americans https://ClinicalTrials.gov/show/NCT01214356 Completed Medical University of South Carolina 2013-07-31
NCT01200394 A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy https://ClinicalTrials.gov/show/NCT01200394 Completed Pfizer 2013-07-31
NCT01191983 A Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) for the Treatment of Chronic Renal Anemia in Participants With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01191983 Completed Hoffmann-La Roche 2018-04-23
NCT01130727 The Effect of Green Tea or Cocoa Extracts in Endothelial Dysfunction in Patients With Diabetes Mellitus https://ClinicalTrials.gov/show/NCT01130727 Completed University of Campinas, Brazil 2012-02-29
NCT01109212 The Effects of Bindarit in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01109212 Completed Aziende Chimiche Riunite Angelini Francesco S.p.A 2008-11-30
NCT01068041 Effects of PH3 in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01068041 Completed PhytoHealth Corporation 2014-07-31
NCT01028287 Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN) https://ClinicalTrials.gov/show/NCT01028287 Completed Southeast Renal Research Institute 2010-12-31
NCT01015937 Effect of Turmeric on Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01015937 Completed Shaheed Faghihi Hospital 2009-06-30
NCT01003236 Evaluating the Renoprotective Effect of Milk Thistle Extract on Patients With Type II Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01003236 Completed Shiraz University of Medical Sciences 2011-10-31
NCT00967629 Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00967629 Completed Icahn School of Medicine at Mount Sinai 2010-02-28
NCT00920764 A Study of Atrasentan on Reducing Albuminuria in Type 2 Diabetic Nephropathy Treated With Renin-Angiotensin System Inhibitors https://ClinicalTrials.gov/show/NCT00920764 Completed AbbVie 2010-04-30
NCT00915200 N-Acetylcysteine and Milk Thistle for Treatment of Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00915200 Completed The University of Texas Health Science Center at San Antonio 2016-04-30
NCT00914524 Study of Olmesartan Medoxomil (CS-866) in Patients With Chronic Glomerulonephritis or Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00914524 Completed Daiichi Sankyo, Inc. 2006-04-30
NCT00893425 Effect of Renin Angiotensin System Blockade on the Fas Antigen (CD95) and Asymmetric Dimethylarginine (ADMA) Levels in Type-2 Diabetic Patients With Proteinuria https://ClinicalTrials.gov/show/NCT00893425 Completed Gulhane School of Medicine 2009-03-31
NCT03869931 Effects of Fenofibrate Therapy in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03869931 Recruiting Singapore General Hospital 2021-04-30
NCT00811889 Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease https://ClinicalTrials.gov/show/NCT00811889 Completed Reata Pharmaceuticals, Inc. 2010-05-31
NCT01667614 Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure https://ClinicalTrials.gov/show/NCT01667614 Completed Tehran University of Medical Sciences 2012-03-31
NCT02914691 Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT02914691 Completed Steno Diabetes Center Copenhagen 2017-07-05
NCT02509624 Pharmacokinetics of GS-4997 in Adults With Normal and Impaired Hepatic Function https://ClinicalTrials.gov/show/NCT02509624 Completed Gilead Sciences 2015-12-31
NCT03889236 Dietary Interventions on Glycocalyx Dimensions in South Asian Patients With Diabetic Nephropathy. https://ClinicalTrials.gov/show/NCT03889236 Recruiting Leiden University Medical Center 2019-12-31
NCT03415074 Could Ketoanalogue-supplemented Low Protein Diet Defer Dialysis in Advanced Diabetic Kidney Disease? (K-DDD) https://ClinicalTrials.gov/show/NCT03415074 Recruiting Anemia Working Group Romania 2022-09-30
NCT00782847 Evaluation Study for the Programme DiaNe for People With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00782847 Completed DiaNe HCM GmbH 2007-01-31
NCT00774904 Adiponectin and Insulin Resistance in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00774904 Completed Health Science Center of Xi’an Jiaotong University 2007-10-31
NCT00754143 Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00754143 Completed FibroGen 2009-12-31
NCT00738660 Efficacy of Telmisartan and the Combination of Telmisartan and Ramipril in type1 Diabetes Patients With Nephropathy https://ClinicalTrials.gov/show/NCT00738660 Completed Postgraduate Institute of Medical Education and Research 2008-05-31
NCT00737126 The Effect of Folic Acid Administration in the Progression of Microalbuminuria https://ClinicalTrials.gov/show/NCT00737126 Completed Hospital Universitario Dr. Jose E. Gonzalez 2005-12-31
NCT00734253 Safety and Efficacy Study of Pyridorin in Patients With Nephropathy Due to Type 2 Diabetes https://ClinicalTrials.gov/show/NCT00734253 Completed NephroGenex, Inc. 2010-08-31
NCT00708981 Combined Diabetes-Renal Multifactorial Intervention In Patients With Advanced Diabetic Nephropathy (ADN) https://ClinicalTrials.gov/show/NCT00708981 Completed John H. Stroger Hospital 2013-10-31
NCT00663949 Assessment of the Effect of Captopril Versus Combination of Captopril and Pentoxifylline on Reducing Proteinuria in Type 2 Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00663949 Completed Shiraz University of Medical Sciences 2007-12-31
NCT00664027 Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00664027 Completed Reata Pharmaceuticals, Inc. 2009-05-31
NCT00594152 Anti-Nephropathic Effects of Chronic Intermittent Intravenous Insulin Therapy (CIIIT) https://ClinicalTrials.gov/show/NCT00594152 Completed Joslin Diabetes Center NA
NCT00565318 Benfotiamine in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00565318 Completed University Medical Center Groningen 2009-06-30
NCT00561704 Adiponectin in Obese Women With T2DN and Effects by RAS Blocker https://ClinicalTrials.gov/show/NCT00561704 Completed Shanghai Jiao Tong University School of Medicine NA
NCT00556465 Efficacy of N-Acetylcysteine in Treatment of Overt Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00556465 Completed Shiraz University of Medical Sciences NA
NCT00552409 Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT00552409 Completed University of Washington 2010-06-30
NCT00544934 Multiple Dose Trial of Anti-glycation Agent GLY-230 in Healthy and Diabetic Subjects https://ClinicalTrials.gov/show/NCT00544934 Completed Glycadia NA
NCT00535925 Nephropathy In Type 2 Diabetes and Cardio-renal Events https://ClinicalTrials.gov/show/NCT00535925 Completed University of Campania “Luigi Vanvitelli” 2011-12-31
NCT00518362 To Compare the Efficacy and Safety of Tripterygium (TW) Versus Valsartan in the Diabetic Nephropathy (DN) https://ClinicalTrials.gov/show/NCT00518362 Completed Nanjing University School of Medicine 2009-09-30
NCT00498537 Spironolactone for Reducing Proteinuria in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00498537 Completed VA Office of Research and Development 2005-12-31
NCT00484068 Chicken-Diet vs. Enalapril to Reduce Albuminuria https://ClinicalTrials.gov/show/NCT00484068 Completed Hospital de Clinicas de Porto Alegre NA
NCT00464880 Effects of Aliskiren, Irbesartan, and the Combination in Hypertensive Patients With Type 2 Diabetes and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00464880 Completed Novartis NA
NCT00446459 Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant. https://ClinicalTrials.gov/show/NCT00446459 Completed University of Washington 2008-11-30
NCT00446251 Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant https://ClinicalTrials.gov/show/NCT00446251 Completed University of Washington 2008-04-30
NCT00438503 Glucose in Dialysis Water in Diabetics With Chronic Renal Failure https://ClinicalTrials.gov/show/NCT00438503 Completed Regional Hospital Holstebro NA
NCT00421733 The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors https://ClinicalTrials.gov/show/NCT00421733 Completed Abbott 2009-06-30
NCT00419835 Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT00419835 Completed University of Sao Paulo 2007-09-30
NCT00364988 Pioglitazone and Losartan Provides Additional Renoprotection https://ClinicalTrials.gov/show/NCT00364988 Completed Shanghai Jiao Tong University School of Medicine 2005-12-31
NCT00363987 Controlled Study to Evaluate Efficacy and Safety of α-KA Tab With Low Protein Diet (LPD) in Delaying the Progress of Type 2 Diabetic Nephropathy (DN) https://ClinicalTrials.gov/show/NCT00363987 Completed Fresenius Kabi 2008-12-31
NCT00362960 Olmesartan Medoxomil and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00362960 Completed Daiichi Sankyo, Inc. NA
NCT00361023 Effects of Losartan on Insulin Sensitivity and Secretion in Type 2 Diabetes and Nephropathy https://ClinicalTrials.gov/show/NCT00361023 Completed Shanghai Jiao Tong University School of Medicine NA
NCT00354341 (ACORD Study) - A Study of NeoRecormon (Epoetin Beta) in Patients With Early Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00354341 Completed Hoffmann-La Roche 2005-07-31
NCT00340678 Renoprotection in Early Diabetic Nephropathy in Pima Indians https://ClinicalTrials.gov/show/NCT00340678 Completed National Institutes of Health Clinical Center (CC) 2012-05-31
NCT00324675 Effects of Rosiglitazone on Renal Hemodynamics and Proteinuria of Type 2 Diabetic Patients With Renal Insufficiency Due to Overt Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00324675 Completed Technische Universität Dresden 2008-12-31
NCT00320970 Angiotensin II Antagonism of TGF-Beta 1 https://ClinicalTrials.gov/show/NCT00320970 Completed Providence Health & Services NA
NCT00320060 Effect of Pyridorin in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00320060 Completed BioStratum NA
NCT00320021 Effect of Pyridorin in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00320021 Completed BioStratum NA
NCT00317954 Spironolactone in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00317954 Completed Steno Diabetes Center Copenhagen NA
NCT00315016 Eplerenone, ACE Inhibition and Albuminuria https://ClinicalTrials.gov/show/NCT00315016 Completed Radboud University 2011-07-31
NCT00312780 Study of XL784 in Patients With Albuminuria Due to Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00312780 Completed Symphony Evolution, Inc. 2007-10-31
NCT00311870 Renoprotective Effect of Nisoldipine and Lisinopril in Type 1 Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00311870 Completed Steno Diabetes Center Copenhagen NA
NCT00296296 Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM) https://ClinicalTrials.gov/show/NCT00296296 Completed Stanford University 2014-10-31
NCT00295555 Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00295555 Completed Yokohama City University Medical Center NA
NCT00287183 6-Month Safety And Efficacy Study Of TTP488 In Patients With Type 2 Diabetes And Persistent Albuminuria https://ClinicalTrials.gov/show/NCT00287183 Completed Pfizer 2009-08-31
NCT00272831 The Use of Cilostazol in Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00272831 Completed Chinese University of Hong Kong 2007-12-31
NCT00253786 Study for the Effectiveness of Intensive Therapy Aiming at a Remission of Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00253786 Completed Okayama University 2014-11-27
NCT00240019 Maximizing the Benefit of Renin-Angiotensin Blocking Drugs in Diabetic Renal Disease. https://ClinicalTrials.gov/show/NCT00240019 Completed Stanford University NA
NCT00237952 Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00237952 Completed Chang Gung Memorial Hospital NA
NCT00222846 Enhancing Adherence in Type 2 Diabetes: The ENHANCE Study https://ClinicalTrials.gov/show/NCT00222846 Completed University of Pittsburgh 2009-12-31
NCT00212901 High Dose Ace Inhibitor Therapy Versus Combination of ACE and ARB Therapy https://ClinicalTrials.gov/show/NCT00212901 Completed Ottawa Hospital Research Institute NA
NCT00171574 Antiproteinuric Effect of Valsartan and Lisinopril https://ClinicalTrials.gov/show/NCT00171574 Completed Novartis 2006-07-31
NCT00168857 A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study) https://ClinicalTrials.gov/show/NCT00168857 Completed Boehringer Ingelheim 2006-06-30
NCT00153088 INNOVATION Study - Telmisartan (Micardis) in Incipient Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00153088 Completed Boehringer Ingelheim 2005-11-30
NCT00153023 1 Year Trial Telmisartan 80 mg Versus Valsartan 160 mg in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy https://ClinicalTrials.gov/show/NCT00153023 Completed Boehringer Ingelheim 2005-12-31
NCT00141453 ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial https://ClinicalTrials.gov/show/NCT00141453 Completed Daiichi Sankyo, Inc. 2008-08-31
NCT00136188 Nitric Oxide (NO) Activity and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00136188 Completed University of Erlangen-Nürnberg Medical School 2011-12-31
NCT00130208 Effect of Sulodexide in Early Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00130208 Completed Keryx Biopharmaceuticals 2008-01-31
NCT00118976 Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT00118976 Completed Steno Diabetes Center Copenhagen NA
NCT00106561 Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney https://ClinicalTrials.gov/show/NCT00106561 Completed Melbourne Health NA
NCT00097955 Safety and Efficacy of Aliskiren When Added to Standardized Losartan and Optimal Antihypertensive Therapy in Patients With Hypertension, Type 2 Diabetes and Proteinuria https://ClinicalTrials.gov/show/NCT00097955 Completed Novartis 2007-04-30
NCT00067678 Soy Protein in Early Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00067678 Completed National Center for Complementary and Integrative Health (NCCIH) NA
NCT00063583 Pirfenidone: A New Drug to Treat Kidney Disease in Patients With Diabetes https://ClinicalTrials.gov/show/NCT00063583 Completed Sharma, Kumar, M.D. 2007-11-30
NCT00044148 The Effect of LY333531 on Protein in the Urine in Patients With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT00044148 Completed Chromaderm, Inc. 2004-04-28
NCT00004266 Drugs for High Blood Pressure and High Cholesterol in American Indians With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT00004266 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 1999-07-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03407989 SWIDINEP a Swiss Diabetic Nephropathy Cohort https://ClinicalTrials.gov/show/NCT03407989 Recruiting Centre Hospitalier Universitaire Vaudois 2022-01-01
NCT03334318 PERL Continuous Glucose Monitoring (CGM) Study https://ClinicalTrials.gov/show/NCT03334318 Active, not recruiting Joslin Diabetes Center 2019-08-31
NCT03155087 PRKAA2 Genetic Polymorphisms and Its Susceptibility to Chinese Type 2 Diabetes Mellitus and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03155087 Completed People’s Hospital of Zhengzhou University 2015-06-30
NCT03137316 Prevalence of Secondary Hyperparathyroidism Among Patients With Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03137316 Completed Benha University 2017-02-28
NCT02996539 Heart Rate Variability and Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients https://ClinicalTrials.gov/show/NCT02996539 Completed First People’s Hospital of Kunming 2015-04-30
NCT02986984 Transformative Research in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02986984 Active, not recruiting University of Pennsylvania 2020-12-31
NCT02625649 Effect of Gastric Bypass Surgery on Diabetes Status and Microvascular Complications in Obese Type 2 Diabetic Patients https://ClinicalTrials.gov/show/NCT02625649 Completed University of Aarhus 2016-12-31
NCT02316522 Epigenetic Contribution to the Pathogenesis of Diabetic Nephropathy in Qatari Population https://ClinicalTrials.gov/show/NCT02316522 Active, not recruiting Weill Medical College of Cornell University 2022-02-28
NCT02299960 Measurement of Endothelial Function and Cardiac Output: New Methods https://ClinicalTrials.gov/show/NCT02299960 Completed Charite University, Berlin, Germany 2015-09-30
NCT02204280 The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT02204280 Completed Hebei Medical University Third Hospital 2015-07-31
NCT02150707 The Differential Effects of Diabetes Therapy on Inflammation https://ClinicalTrials.gov/show/NCT02150707 Completed University College Dublin 2015-12-31
NCT02145572 Metabolomic Profiling in Adolescents With Obesity and Diabetes https://ClinicalTrials.gov/show/NCT02145572 Active, not recruiting University of California, San Diego 2019-04-30
NCT02001532 Arterial Stiffness and Complication Risk in Type 2 Diabetes https://ClinicalTrials.gov/show/NCT02001532 Completed University of Aarhus 2016-05-31
NCT01845870 Serum 1,25-dihydroxyvitamin D Levels in Type 2 Diabetes Mellitus Patients With Different Levels of Albuminuria https://ClinicalTrials.gov/show/NCT01845870 Completed Tianjin Medical University General Hospital 2013-04-30
NCT01810822 Sex-specific Association With Kidney Disease https://ClinicalTrials.gov/show/NCT01810822 Completed University of Sao Paulo General Hospital 1994-05-31
NCT01768611 SLC2A1 Variants and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01768611 Completed University of Sao Paulo General Hospital 2012-10-31
NCT03865914 Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03865914 Recruiting Chinese PLA General Hospital 2021-03-01
NCT01371955 Impact of c242T Polymorphism of p22phox in Diabetic type1 Nephropathy https://ClinicalTrials.gov/show/NCT01371955 Completed University Hospital, Grenoble 2013-03-31
NCT04235621 A Study to Understand the Genetics and Clinical Course of Focal Segmental Glomerulosclerosis (FSGS), Treatment-Resistant Minimal Change Disease (TR-MCD), and Diabetic Nephropathy (DN) https://ClinicalTrials.gov/show/NCT04235621 Recruiting Goldfinch Bio, Inc. 2021-06-30
NCT04176276 Determining Serum and Urinary Levels of miRNA 192 and miRNA 25 in Patients With and Without Type 2 Diabetes. https://ClinicalTrials.gov/show/NCT04176276 Completed University of Pisa 2019-12-31
NCT04119167 Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians https://ClinicalTrials.gov/show/NCT04119167 Recruiting Chang Gung Memorial Hospital 2021-07-30
NCT04074668 Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance https://ClinicalTrials.gov/show/NCT04074668 Recruiting University of Colorado Denver School of Medicine Barbara Davis Center 2021-10-31
NCT04029402 Molecular Analysis of Diabetic Kidney Disease Biopsies https://ClinicalTrials.gov/show/NCT04029402 Recruiting St. Michael’s Hospital, Toronto 2022-12-31
NCT03945747 MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT03945747 Recruiting University of Colorado, Denver 2021-07-31
NCT03921216 Cholesterol Metabolism in Plasma and Interstitial Fluid Among Subjects Undergoing Hemodialysis. https://ClinicalTrials.gov/show/NCT03921216 Recruiting Karolinska University Hospital 2020-12-31
NCT03716401 Prognostic Imaging Biomarkers for Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03716401 Recruiting University of Leeds 2020-09-01
NCT03690180 Hypomagnesemia and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT03690180 Completed Fayoum University 2018-01-30
NCT03621384 Association of BsmI Polymorphisms in Vitamin D Receptor Gene With Diabetic Kidney Disease https://ClinicalTrials.gov/show/NCT03621384 Completed Indonesia University 2015-03-31
NCT03509454 PeRsOnalising Treatment Of Diabetic Nephropathy: https://ClinicalTrials.gov/show/NCT03509454 Completed Steno Diabetes Center Copenhagen 2017-10-01
NCT01163591 To Assess the Accuracy of the eZscan Study in the Screening for Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT01163591 Completed Chinese University of Hong Kong 2009-10-31
NCT01069549 Association of AGTR1 and ACACB Gene Polymorphism and Diabetic Nephropathy in Type 2 Diabetes https://ClinicalTrials.gov/show/NCT01069549 Completed Postgraduate Institute of Medical Education and Research 2011-04-30
NCT01377688 Personalized Diabetic Kidney Disease Risk Info to Initiate and Maintain Health Behavior Changes https://ClinicalTrials.gov/show/NCT01377688 Completed Duke University 2014-04-30
NCT03909269 Glycaemic Markers in Persons With Type 2 Diabetes on Haemodialysis https://ClinicalTrials.gov/show/NCT03909269 Completed Rigshospitalet, Denmark 2020-04-01
NCT00419484 Effect of Pioglitazone on Cardiovascular Outcome on Higashi-Saitama Trial in Patients With Type 2 Diabetes https://ClinicalTrials.gov/show/NCT00419484 Completed Dokkyo Medical University NA
NCT00353600 Delaying the Progression of Diabetic Nephropathy in Pima Indians https://ClinicalTrials.gov/show/NCT00353600 Completed National Institutes of Health Clinical Center (CC) NA
NCT00301249 The Family Investigation of Nephropathy and Diabetes Study https://ClinicalTrials.gov/show/NCT00301249 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2006-12-31
NCT00067886 Matrix Metalloproteinases and Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT00067886 Completed Arkansas Children’s Hospital Research Institute 2008-12-31
NCT00024921 The Genetics of Kidneys in Diabetes (GoKinD) Study https://ClinicalTrials.gov/show/NCT00024921 Completed National Center for Research Resources (NCRR) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT01802034 Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID) https://ClinicalTrials.gov/show/NCT01802034 Recruiting The Rogosin Institute 2022-08-31
NCT04403945 The Predictive Value of Sidestream Dark Field Imaging in Diabetic Nephropathy https://ClinicalTrials.gov/show/NCT04403945 Recruiting Third Military Medical University 2020-09-01
NCT04380584 Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients. https://ClinicalTrials.gov/show/NCT04380584 Completed Cairo University 2020-03-20
NCT03859817 Observational Study to Evaluate the Relationship Between Ketonemia and Renal Function in the Diabetic Patient https://ClinicalTrials.gov/show/NCT03859817 Active, not recruiting University of Milan 2020-04-18